This paper offers a roadmap to face challenges in the housing sector and secure the nation’s future. The Obama Administration’s new Affirmatively Furthering Fair Housing rule, Affordable Care Act investments in health promotion, the recent Supreme Court victory for advocates challenging exclusionary housing policies, the deepening engagement of philanthropy, the growing demand for investments that improve sustainability and climate resiliency, and robust organizing by communities—all this adds up to the best opportunity in years to transform the nation’s housing infrastructure into an engine of health, opportunity, and prosperity for all.